Compositions and methods for combination therapy with dengue virus and dendritic cells
AssigneePrimevax Immuno-Oncology, Inc.
InventorBruce W. Lyday
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Abstract
Described herein are compositions and methods for treating cancer through the combination of tumor antigen-pulsed dendritic cells and Dengue Virus. The combination of the two forms of therapeutic intervention provides enhanced tumor cell reduction compared to either alone. The cancer targeted by compositions and methods described herein may be a solid cancer or blood cancer.
Claims9
A method for reducing or treating cancer in a subject in need thereof, comprising subcutaneously administering to the subject an effective amount of a Dengue Virus as an adjuvant to an immunotherapy for treatment of cancer, wherein the Dengue Virus is present in an amount of 103 pfu/ml to 108 pfu/ml.
Dependencies are inferred from the claim text.