Water-soluble meloxicam granules
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsStefan Henke, Martin A. Folger, Jens Lehmann, Diana C. Keilhofer, Hans-Juergen Kroff, Nina Herz
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Abstract
A method of treating animals includes administering water soluble granules to an animal, where the water soluble granules include meloxicam, salt forming agent operable to form a meloxicam salt, a binder, and a carrier.
Claims14
A method of treating animals comprising administering free flowing water soluble granules to a non-human animal, the free flowing water soluble granules consisting of:
- meloxicam;
- a salt forming agent which forms the meglumine, sodium, potassium, or ammonium salt of meloxicam;
- a binder;
- a sugar or sweetener;
- a carrier;
- and
- optionally a flavoring agent;
- wherein 5 g of said granules dissolve in 100 mL of demineralized water in about 1 minute to form a clear solution, and the water soluble granules do not include cyclodextrin.
A method of treating animals comprising administering free flowing water soluble granules to a non-human animal, wherein each granule comprises:
- a carrier comprising glucose, lactose, or sorbitol;
- a first granulating composition sprayed on to the carrier so as to form a combined carrier-first granulating composition, the first granulating composition comprising meloxicam, a salt forming agent which forms the meglumine, sodium, potassium, or ammonium salt of meloxicam, a binder, and optionally a component comprising a flavoring agent and/or a sweetener;
- and
- a second granulating composition sprayed on to coat the combined carrier-first granulating composition, the second granulating composition comprising the binder and the component comprising the flavoring agent and/or the sweetener.
Dependencies are inferred from the claim text.