Sodium channel blockers for skin disorders
AssigneeParion Sciences, Inc.
InventorsMichael Ross Johnson, William Robert Thelin, Richard C. Boucher
Life of this patent
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Abstract
Provided are methods of treating a variety of disorders of the skin with inhibitors of the epithelial sodium channel (ENaC). The inhibitors are represented by formula (I)-(IV): where R is defined herein.
Claims16
A method of treating at least one disorder of the skin selected from the group consisting of psoriasis, an inflammatory disease of the skin, a wound, a lesion or ulcer of the skin, eczema, lupus, rosacea, a skin rash, a cold sore, shingles or acne in a human in need thereof comprising administering to the human an amount effective to treat the skin disorder of an active agent comprising at least one compound represented by formula (I)-(IV):
- Wherein
- or a pharmaceutically acceptable salt thereof.
A method of minimizing scarring in a human in need thereof comprising administering to the human an effective amount of a compound represented by formula (I)-(IV):
- Wherein
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.