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US 9,849,119 B2Granted
Opioid receptor ligands and methods of using and making same
AssigneeTrevena, Inc.
InventorsDennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
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Abstract
This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
Claims36
A compound having a formula of
- or a pharmaceutically acceptable salt thereof, wherein:
- R21 and R22 are independently H or CH3;
- D1 is an optionally substituted aryl;
- B3 is H or optionally substituted alkyl;
- and
- B5 is an optionally substituted thiophenyl,
- wherein a hydrogen is replaced with a deuterium.
4 more elements
A compound having a formula of
- or a pharmaceutically acceptable salt thereof, wherein a hydrogen is replaced with a deuterium.
Dependencies are inferred from the claim text.