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US 9,849,080 B2Granted
Transdermal compositions of ibuprofen and methods of use thereof
AssigneeAponia Laboratories, Inc.
InventorsHaigang Chen, Gareth Winckle, Christopher Riley
Life of this patent
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Abstract
A transdermal composition comprising ibuprofen or salts thereof and a gelling agent which can be used for the treatment of such disorders as pain, inflammation, arthritis, muscle spasm and associated symptoms in humans and animals.
Claims5
A composition for transdermal administration of ibuprofen or a salt thereof comprising:
- S(+)-ibuprofen, or a salt thereof, wherein about 5% by weight of the composition is S(+)-ibuprofen;
- hydroxypropyl cellulose present in an amount between about 1% and about 5% by weight of the composition;
- isopropyl myristate present in an amount between about 0.1% and about 5% by weight of the composition;
- propylene glycol present in an amount between about 10% and about 20% by weight of the composition;
- a lower alkyl alcohol selected from the group consisting of ethanol, isopropyl alcohol, and mixtures thereof, and the lower alkyl alcohol is present in an amount between about 35% and about 60% by weight of the composition;
- and
- water;
- wherein the composition has an apparent pH in the range from 4.0 to 7.0.
5 more elements
Dependencies are inferred from the claim text.