Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients

A packaged pharmaceutical composition comprising:

• A glass pharmaceutical container and a pharmaceutical composition contained within the glass pharmaceutical container, wherein the pharmaceutical composition comprises:
• Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine, Hepatitis A Vaccine, Hepatitis B Vaccine (Recombinant), Hepatitis A & Hepatitis B (Recombinant) Vaccine, albiglutide, MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (astuprotimut-R), GSK2402968 (drisapersen), or HZ/su (herpes zoster vaccine) and a pharmaceutically acceptable excipient;
• wherein the glass pharmaceutical container comprises a glass composition comprising
• SiO2 in a an amount greater than or equal to 72 mol. % and less than or equal to 78 mol. %;
• alkaline earth oxide comprising both MgO and CaO, wherein CaO is present in an amount up to about 1.0 mol. %, and a ratio (CaO (mol. %)/(CaO (mol. %)+MgO (mol. %))) is less than or equal to 0.5;
• X mol. % Al2O3, wherein X is greater than or equal to 5 mol. % and less than or equal to 7 mol. %;
• Y mol. % alkali oxide, wherein the alkali oxide comprises Na2O in an amount greater than 8 mol. %;
• and
• a ratio of a concentration of B2O3 (mol. %) in the glass container to (Y mol. %−X mol. %) is less than or equal to 0.3.