System and method for use in erectile dysfunction conditions

A non-invasive system for inducing penile blood vessel and penile erectile tissue volume changes, the system comprising:

• a cylindrical socket having interior walls and an open end;
• at least one circumferential sealing element within the cylindrical socket, wherein a pressurizable compartment is defined by the sealing element and the interior walls;
• a control unit and a processing unit;
• at least one pressure pump operationally connected to the control unit and the processing unit, wherein the compartment when sealed is in one of two states:
• a first state wherein the compartment is in positive pressure, and a second state, wherein the compartment is in sub-atmospheric pressure;
• at least one pressure reservoir, each reservoir fluidly connectable to said compartment and to one of the pressure pumps;
• at least one mechanical switching element operationally connected to the control unit and the processing unit and to at least one of the pressure reservoirs;
• at least one measuring element capable of measuring a pulse-wave or a cardiac cycle, wherein the control unit and the processing unit are capable of receiving a signal from the measuring elements and determining a time, rate and shape of pulse-waves, and wherein said control unit and said processing unit are gated by the at least one measuring element to control said mechanical switching elements such as to switch fluid connectivity of the pressurizable compartment to the reservoirs and alternately switch the sealed compartment between the first state and the second state, and further comprising a pressure or force application controlling mechanism operationally connected to the control unit and the processing unit and the measuring elements, and programmed to control the positive pressure or applied force and sub-atmospheric pressure according to an amplitude of the measured pulse or pulse-wave.

A non-invasive system for inducing penile blood vessel and penile erectile tissue volume changes, the system comprising:

• a cylindrical socket having interior walls and an open end;
• at least one circumferential sealing element within the cylindrical socket, wherein a pressurizable compartment is defined by the sealing element and the interior walls;
• a control unit and a processing unit;
• at least one pressure pump operationally connected to the control unit and the processing unit, wherein the compartment when sealed is in one of two states:
• a first state wherein the compartment is in positive pressure, and a second state, wherein the compartment is in sub-atmospheric pressure;
• at least one pressure reservoir, each reservoir fluidly connectable to said compartment and to one of the pressure pumps;
• at least one mechanical switching element operationally connected to the control unit and the processing unit and to at least one of the pressure reservoirs;
• at least one measuring element capable of measuring a pulse-wave or a cardiac cycle, wherein the control unit and the processing unit are capable of receiving a signal from the measuring elements and determining a time, rate and shape of pulse-waves, and wherein said control unit and said processing unit are gated by the at least one measuring element to control said mechanical switching elements such as to switch fluid connectivity of the pressurizable compartment to the reservoirs and alternately switch the sealed compartment between the first state and the second state, wherein the switching of pressures or applied force is gated by a fixed time delay from an ECG-R wave as predetermined with respect to the measuring elements.

A non-invasive system for inducing penile blood vessel and penile erectile tissue volume changes, the system comprising:

• a cylindrical socket, having interior walls and an open end;
• at least one circumferential sealing element within the socket,
• wherein a compartment is defined by the sealing element and the interior walls;
• a control unit and a processing unit;
• a linear stepper motor connected to said control unit and the processing unit;
• at least one force exertion element capable of applying force onto said interior walls;
• a one-way valve connectable to said compartment and capable of removing air trapped by said at least one force exertion element;
• at least one measuring elements capable of measuring a pulse-wave or a cardiac cycle, wherein the control unit and the processing unit are capable of receiving a signal from the measuring elements and determining a time, rate and shape of pulse-waves, and wherein said control unit and said processing unit are gated by the at least one measuring element to control said linear stepper motor.

A non-invasive system for inducing penile blood vessel and penile erectile tissue volume changes, the system comprising:

• a cylindrical socket having interior walls and an open end;
• at least one circumferential sealing element within the socket,
• wherein a compartment is defined by the sealing element and the interior walls;
• a control unit and a processing unit;
• a linear stepper motor, connected to said control unit and said processing unit;
• at least one force exertion element capable of applying force onto said interior walls;
• at least one pressure pump operationally connected to the control and processing unit;
• at least one pressure reservoir, each reservoir fluidly connectable to said compartment and to one of the pressure pumps;
• at least one mechanical switching element operationally connected to the control unit and the processing unit and to at least one of the pressure reservoirs;
• at least one measuring element capable of measuring a pulse-wave or a cardiac cycle, wherein the control unit and the processing unit is capable of receiving a signal from the measuring elements and determining a time, rate and shape of pulse-waves, and wherein said control unit and said processing unit is gated by the at least one measuring element to control said linear stepper motor and said at least one pressure pump.

Inducing cyclic augmented penile blood volume changes in a penis of a subject comprising:

• providing a cylindrical socket having interior walls, an open end, at least one circumferential sealing element within the socket, a means for inducing cyclic augmented penile blood volume changes in the penis of the subject;
• wherein a pressurizable compartment is defined by the sealing element and the interior walls;
• a control unit and a processing unit;
• at least one mechanical switching element operationally connected to the control unit and the processing unit and at least one measuring element capable of measuring a pulse-wave or a cardiac cycle;
• sealing the compartment by inserting the penis through the sealing element into the socket;
• operationally coupling the measurement elements to the subject;
• sending at least one signal from the measuring elements to the control unit and the processing unit, and determining a time, rate and shape of pulse-waves from the subject;
• the at least one measuring element gating said control unit and the processing unit to alternately apply with the means for inducing cyclic augmented penile blood volume changes, such as to apply positive force or pressure to the penis, and sub-atmospheric pressure to said compartment, such as to apply sub-atmospheric pressure to the penis,
• wherein said alternating of phases of sub-atmospheric pressure, and above atmospheric pressure or applied force to the penile tissues, is gated by the timing and/or amplitude and/or rate and/or shape of a peripheral pulse-wave of the subject, and
• wherein said pulse-wave amplitude cycle is preceded by a predetermined delay period by ECG signal markers.