Ingestible delivery systems and methods

An ingestible delivery system configured to mimic a naturally formed bolus of food to facilitate ingestion by a patient, the delivery system comprising:

• a bio-compatible material encasing a gastric device in a compressed configuration, where the bio-compatible material extends from the gastric device to prevent the patient from sensing the gastric device during ingestion and forms a body configured to reduce a gagging reflex of the patient, where the bio-compatible material is elastically deformably compliant;
• the body having a front, a first side, a second side, and a rear, the body comprising:
• a bottom surface having a smoothly continuous surface extending from the front of the body to the rear of the body;
• a top surface opposite to the bottom surface, the top surface having a bulge region, where the body has a maximum thickness as measured between the top and bottom surface at the bulge region, where the top surface comprises a front tapering surface that smoothly tapers from the bulge region to the front of the body and a rear tapering surface that smoothly tapers from the bulge region to the rear of the body, such that a thickness of the body decreases from the bulge region along both the front tapering surface and rear tapering surface and the thickness of the body decreases from the bulge region towards the first and second sides of the body, where a length of the front tapering surface is greater than a length of the rear tapering surface;
• and
• the gastric device being releaseable from the bio-compatible material subsequent to ingestion such that the gastric device can assume an expanded profile.