Implant and method for manufacturing same
AssigneeBIOTRONIK SE & Co. KG
InventorsRobert Schmiedl, Matthias Gratz, Max Schaldach, Volker Lang
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Abstract
A method for manufacturing an implant and an implant, in particular an intraluminal endoprosthesis, including a body having a coating on at least a portion of the surface thereof, and the degradation of which can be influenced from the outside in a targeted manner, the method having the following steps: a) providing an implant body, and b) applying a coating to the surface of the implant body, wherein the coating comprises unfilled cavities, preferably in the form of microbubbles (2).
Claims7
A method for manufacturing a biodegradable implant comprising the following steps:
- a) providing an implant body;
- b) applying a pharmaceutical layer to the implant body, wherein the pharmaceutical layer comprises a pharmaceutically active substance;
- and
- c) applying a coating comprising rupturable, unfilled microbubbles over the pharmaceutical layer, wherein the microbubbles are configured to rupture by way of ultrasonic excitation.
A biodegradable implant comprising a body at least partially coated with a pharmaceutical layer and over the pharmaceutical layer is a coating of microbubbles filled with inert gas and configured to rupture by way of ultrasonic excitation.
A biodegradable implant comprising a body at least partially coated with a pharmaceutical layer coated with microbubbles filled with inert gas and configured to rupture by way of ultrasonic excitation, characterized in that the microbubbles are attached to a surface of the implant body using an embedding matrix, wherein the matrix comprises at least one material selected from the group consisting of a polymer, a lipid, a citrate-based softening agent, a protein and a peptide.
Dependencies are inferred from the claim text.