Clinical assessment of fragile bone strength
AssigneeO.N.Diagnostics, LLC
InventorsDavid L. Kopperdahl, Paul Frederick Hoffmann, David Choen Lee, Garry Thomas Hayeck, Tony M. Keaveny
Life of this patent
Estimating the term…
Abstract
A system and method for the use of the results from a structural analysis of a patient's bone from a clinical scan, to be used clinically to manage patients in a widespread and consistent fashion.
Claims9
A computer-implemented method specifying an interventional threshold value of a bone strength parameter of a population data set for a plurality of subjects, each of the subjects including a bone portion, the interventional threshold value providing an indication of a fragile-bone-strength condition, comprising:
- deriving, using a finite element analysis, a bone strength value for the bone strength parameter for each subject in the plurality of subjects;
- receiving a bone mineral density (BMD) value for each subject of the plurality of subjects;
- pairing, for each particular subject in the plurality of subjects, said bone strength value and said BMD value to produce a set of paired measurements of bone strength and BMD for the plurality of subjects;
- and
- specifying the value for the bone strength interventional threshold responsive to an established BMD interventional threshold value for osteoporosis and a statistical correspondence of said set of paired measurements.
A non-transitory computer readable storage medium storing a program therein, for execution by a processor to generate a classification of a fragile-bone-strength condition for a patient by performing the method of:
- deriving, using a finite element analysis, a bone strength value of a bone strength parameter for a bone portion of the patient;
- receiving a predetermined interventional threshold value for the fragile-bone-strength condition for said bone strength parameter;
- classifying the patient for the fragile-bone-strength condition, which produces a fragile-bone-strength classification responsive to a processor-implemented comparison of said bone strength value and said predetermined interventional threshold value.
Dependencies are inferred from the claim text.