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US 9,845,332 B2Granted
Neprilysin inhibitors
AssigneeTheravance Biopharma R&D IP, LLC
InventorsRoland Gendron, Melissa Fleury, Adam D. Hughes
Life of this patent
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Abstract
In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
Claims1
(2R,4R)-5-Biphenyl-4-yl-2-hydroxy-4-[(1-hydroxy-1H-[1,2,3]triazole-4-carbonyl)-amino]-pentanoic acid or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.