6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof

A compound of formula 1 or pharmaceutically acceptable salts thereof

• wherein
• substituent ‘S’ is selected from the group consisting of formula Ia, Ib, Ic, IIa, IIb and IIc;
• wherein,
• ‘G’ is selected from the group consisting of H, CH2OR1, OR1 and R1;
• ‘Z’ is selected from the group consisting of O, S and NR2;
• ‘n’ is any number from 0 to 2;
• ‘M’ is selected from the group consisting of O, S, NR2 and CR3R4;
• R, R1 and R2 are each independently selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, phenyl, substituted phenyl, heterocyclic and substituted heterocyclic group selected from the group consisting of pyridyl, triazolyl, triazinyl, pyrimidinyl, pyridazinyl, oxazolyl, furanyl, benzofuranyl, thiophenyl, pyrrolyl, imidazoyl, thiazoyl, quinolinyl, isoquinolinyl, benzooxazolyl and benzothiazolyl;
• and
• R3 and R4 are each independently selected from the group consisting of H, alkyl, substituted alkyl, alkoxyl, substituted alkoxyl, phenyl, substituted phenyl, phenoxyl, substituted phenoxyl, heterocyclic and substituted heterocyclic group selected from the group consisting of pyridyl, triazolyl, triazinyl, pyrimidinyl, pyridazinyl, oxazolyl, furanyl, thiophenyl, pyrrolyl, imidazoyl and thiazoyl.