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US 9,845,295 B2Granted
Triphenylethylene compounds and uses thereof
AssigneePurdue Research Foundation
InventorsMark S Cushman, Wei Lv, Li-Ming Zhao
Life of this patent
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Abstract
Triphenylethylene compounds of formula (II) as dual aromatase inhibitors and selective estrogen receptors modulators are described. Also described are methods for treating patients of breast cancers, and patients of breast cancer comorbid with osteoporosis, using the described triphenylethylence compounds or pharmaceutical formulations thereof.
Claims9
A triphenylethylene compound of the formula (II)
- wherein:
- R2 is an amino, hydroxyl, nitro, halo, cyano, or hydrogen;
- R3 is an amino, hydroxyl, nitro, halo, cyano, or hydrogen;
- and
- R4 is an amino, hydroxyl, nitro, halo, cyano, C1-C6 alkoxy, or hydrogen.
2 more elements
Dependencies are inferred from the claim text.