Apparatus and platform for detection of allergen
AssigneeNational Tsing Hua University
InventorsGwo-Bin Lee, Wen-Yen Huang
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Abstract
Provided is an allergen detecting apparatus that can combine with an allergen microarray chip, and the apparatus comprises a microfluidic chip and a clamping unit. The allergen microarray chip can be any commercial chip and a reaction region of the microfluidic chip is configured to fit tightly with a microarray region of the allergen microarray chip allowing a sample or a reagent to contact with a protein allergen disposed on the microarray region. The present invention also provides a platform comprising a control system configured to automatically perform the mixing/binding reactions of the antibody/antigen in the apparatus of the present invention to achieve a faster, more cost-effective, and accurate detection of allergens.
Claims13
An allergen detecting apparatus for incorporating an allergen microarray chip having a microarray region, comprising:
- a microfluidic chip having an air control layer and a fluid channel layer, wherein the air control layer comprises at least an air control inlet, and the fluid channel layer comprises at least a liquid injection port and a reaction region;
- and
- a clamping unit having a housing space for accommodating the microfluidic chip, a cover comprising at least a side protrusion, and at least a clamping member for fixing the microfluidic chip to allow the reaction region to align and tightly fit with the microarray region, wherein the clamping member comprises a recess corresponding to the side protrusion and a swing buckle for clipping the side protrusion.
Dependencies are inferred from the claim text.