Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment

A method for inducing transient hyperthermia in a pathogen target, said method comprising the following steps:

• a) generating a magnetic field;
• b) producing a nanoparticle-sized magnetic absorption enhancer exhibiting a controlled response to said magnetic field by:
• i) providing a magnetic material having an inductive thermal response to said magnetic field;
• ii) embedding said magnetic material in a coating that conforms to a predetermined shape complementary to the shape of at least one other magnetic absorption enhancer, thereby enabling a controlled mechanical response of said magnetic absorption enhancer to said magnetic field;
• and
• iii) providing a targeting moiety for specific binding of said magnetic absorption enhancer to a pathogen target;
• c) delivering said magnetic absorption enhancer to a region comprising said pathogen target for specific binding to said pathogen target;
• wherein said controlled response comprises said inductive thermal response for applying a high temperature transient to said pathogen target and said controlled mechanical response comprises an interaction between said magnetic absorption enhancer and said at least one other magnetic absorption enhancer for limiting collateral damage to healthy tissue.