Pluripotent stem cell that induces repair and regeneration after myocardial infarction

A method for treating a myocardial infarction in a subject in need thereof, the method comprising:

• administering to said subject a cell preparation containing a cell fraction comprising a population of pluripotent stem cells positive for SSEA-3, wherein the population of pluripotent stem cells is isolated from mesenchymal tissue or cultured mesenchymal cells by selecting for SSEA-3 positive cells, wherein the population of pluripotent stem cell is concentrated, wherein the pluripotent stem cells have a plurality of properties comprising:
• (i) CD105-positivity;
• (ii) low or absent telomerase activity;
• (iii) ability to differentiate into embryonic endoderm, ectoderm, and mesoderm germ layers;
• (iv) absence of neoplastic proliferation;
• and
• (v) ability to self-renew, and wherein the size of the myocardial infarction in the subject is reduced in comparison to a control subject that did not receive said cell preparation, thereby treating a myocardial infarction in a subject in need thereof.