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US 9,844,526 B2Granted
Methods and compositions for improving microvascular function, suppressing cyclooxygenase activity, reducing platelet aggregation and increasing levels of resveratrol in plasma
AssigneeGateway Health Alliances, Inc.
InventorsShil Kothari, Gary Troxel
Life of this patent
Estimating the term…
Abstract
Methods of increasing the plasma concentration of resveratrol in a mammal in need thereof by administering to a mammal in need thereof an effective amount of trans-resveratrol and arginine for a period of at least two weeks.
Claims13
A method of increasing the plasma concentration of resveratrol in a mammal in need thereof, the method comprising:
- providing to a mammal in need of increased plasma concentration of resveratrol 10mg to 5000 mg daily of a resveratrol and arginine conjugate for a period of at least two weeks;
- wherein the resveratrol and arginine conjugate increases the plasma concentration of resveratrol of the mammal from about 1.6 μM to about 3.63 μM within about one hour of providing resveratrol and arginine conjugate to the mammal.
A method comprising:
- providing a mammal in need of increased plasma concentration of resveratrol 10 mg to 5000 mg daily of a resveratrol and arginine conjugate for a period of at least one week;
- wherein the resveratrol and arginine conjugate increases the plasma concentration of resveratrol of the mammal from about 1.6 μM to about 3.63 μM within about one hour of providing resveratrol and arginine conjugate to the mammal.
A method comprising:
- administering to a mammal in need of increased plasma concentration of resveratrol 10 mg to 5000 mg daily of a resveratrol and arginine conjugate for a period of at least two weeks;
- wherein the resveratrol and arginine conjugate increases the plasma concentration of resveratrol of the mammal from about 0.21 μM to about 2.89 μM within about 30 minutes of providing resveratrol and arginine conjugate to the mammal.
Dependencies are inferred from the claim text.