Sigma ligands for use in the prevention and/or treatment of post-operative pain
AssigneeLaboratorios de Dr. Esteve S.A.
InventorsJosé Miguel Vela Hernández, Daniel Zamanillo-Castanedo, Margarita Puig Riera de Conias
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Abstract
The invention refers to the use of a sigma ligand, particularly a sigma ligand of formulae (I), (II) or (III) to prevent and/or treat acute and chronic pain developed as a consequence of surgery, especially superficial and/or deep pain secondary to surgical tissue injury, and peripheral neuropathic pain, neuralgia, allodynia, causalgia, hyperalgesia, hyperesthesia, hyperpathia, neuritis or neuropathy secondary to surgical procedure.
Claims10
A method of treatment of postoperative pain developed as a consequence of surgery of a patient, which comprises administering to the patient an amount of a sigma ligand effective alone to treat postoperative pain developed as, a consequence of surgery of the patient, wherein the sigma ligand is 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl} morpholine or a pharmaceutically acceptable salt, isomer or solvate thereof.
Dependencies are inferred from the claim text.