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US 9,844,214 B2Granted
Alpha connexin C-terminal (ACT) peptides for use in transplant
AssigneeMUSC Foundation for Research Development
InventorsGautam Ghatnekar, Robert Gourdie, Jane Jourdan
Life of this patent
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Abstract
The present disclosure provides compositions and methods for treating or preventing macular degeneration in a subject. The disclosure also provides compositions and methods for preserving organs and tissues for transplantation, and for preventing cellular injury in organs or in subjects.
Claims31
A method of inhibiting cellular injury in an organ comprising incubating the organ with a solution comprising an isolated polypeptide consisting of the carboxy terminal most 4 to 30 contiguous amino acids of an alpha connexin, or a conservative variant thereof.
Dependencies are inferred from the claim text.