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AssigneeRepublic of Korea (Management: Rural Development Administration)
InventorsSo Hyeon Baek, Woon Chul Shin, Young Jun Mo, Bo Kyong Kim, Seong Tshool Hong, Sun Yeou Kim, Soon Jong Kweon
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The present invention relates to resveratrol-enriched transgenic rice for biosynthesizing resveratrol at high concentration, in which resveratrol synthase genes are expressibly inserted into the 12th chromosome of natural rice, and seed of rice produced therefrom. Further, the present invention relates to a health functional food composition, an animal feed composition, and a pharmaceutical composition for preventing and improving a metabolic disease, including seed of rice produced from the resveratrol-enriched transgenic rice for biosynthesizing resveratrol, in which resveratrol synthase genes are expressibly inserted into the 12th chromosome of natural rice. The seed of rice produced from resveratrol-enriched transgenic rice into which resveratrol synthase genes are inserted, containing high a concentration of resveratrol of the present invention exhibits remarkably superior effects compared to when the same amount of resveratrol is simply ingested. Further, since rice is produced in the form to be used directly as food without an additional process of separating or extracting resveratrol, it may be widely used as food, feed, and medical supplies for preventing and improving a metabolic disease.
Resveratrol-enriched transgenic rice for biosynthesizing resveratrol, wherein two copies of a resveratrol synthase gene are expressibly inserted in an opposing direction from each other at the same location after the 572nd base in the region of a nucleotide sequence represented by SEQ ID NO:
A health functional food composition for preventing and improving a metabolic disease, comprising seed of rice produced from the resveratrol-enriched transgenic rice for biosynthesizing resveratrol, wherein two copies of a resveratrol synthase gene are expressibly inserted in an opposing direction from each other at the same location after the 572nd base in the region of a nucleotide sequence represented by SEQ ID NO:
An animal feed composition for preventing and improving a metabolic disease, comprising seed of rice produced from the resveratrol-enriched transgenic rice for biosynthesizing resveratrol, wherein two copies of a resveratrol synthase gene are expressibly inserted in an opposing direction from each other at the same location after the 572nd base in the region of a nucleotide sequence represented by SEQ ID NO:
A pharmaceutical composition for preventing and improving a metabolic disease, comprising seed of rice produced from the resveratrol-enriched transgenic rice for biosynthesizing resveratrol, wherein two copies of a resveratrol synthase gene are consecutively and expressibly inserted in an opposing direction from each other at the same location after the 572nd base in the region of a nucleotide sequence represented by SEQ ID NO:
Dependencies are inferred from the claim text.