Crystalline form of cefamandole nafate compound, preparation and preparing method thereof

A method for preparing a crystalline form of Cefamandole Nafate having an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ at 4.0±0.2, 4.7±0.2, 6.2±0.2, 7.5±0.2, 9.9±0.2, 10.8±0.2, 14.5±0.2, 15.8±0.2, 16.3±0.2, 17.4±0.2, 18.1±0.2, 19.2±0.2, 20.1±0.2, 21.4±0.2, 22.2±0.2, 22.8±0.2, 23.9±0.2, 24.9±0.2, 30.1±0.2, and 34.1±0.2 and a differential scanning calorimetry thermogram (DSC) having an endothermic peak at 165±2° C., characterized in that:

• adding Cefamandole Nafate in solid state to an organic solvent to form a suspension with a concentration of 0.04˜0.3 g/ml, stirring the suspension at 40˜50° C., then cooling to 5˜15° C. and stirring, and suction filtrating the obtained suspension, the resulting filer cake is Cefamandole Nafate as wet product, which is dried to constant weight to provide the crystalline form of Cefamandole Nafate.