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US 9,816,114 B2Granted
Recombinant host cells for the production of malonate
AssigneeLygos, Inc.
InventorsJeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
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Abstract
Systems and methods for the production of malonate in recombinant host cells.
Claims23
A recombinant Pichia kudriavzevii cell that comprises a heterologous malonyl-CoA hydrolase selected from the group consisting of:
- a. SEQ ID Nos:
- 46, 49, 51, or 52, wherein Xaa is selected from the group consisting of A, D, R, H, K, S, T, N, Q, and Y;
- b. SEQ ID Nos:
- 45, 48, or 50, wherein Xaa is selected from the group consisting of A, D, R, H, K, S, T, N, Q, and Y;
- and
- c. SEQ ID No:
- 47, wherein Xaa is S.
4 more elements
Dependencies are inferred from the claim text.