(3-alkylthio)propenoic acid-derived compounds and their application in cosmetics
AssigneeExsymol
InventorMarie-Christine Seguin
Life of this patent
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Abstract
The present invention relates to compounds of general formula (I): wherein Y, R1, R2 and R3 are as defined in the specification. The invention also relates to cosmetic or dermocosmetic composition containing such compounds. The compounds according to the invention are useful as photoprotective agents.
Claims19
A compound represented by the following general formula (I):
- wherein:
- Y═S or SO;
- R1 is a linear or branched C1-C4 alkyl group;
- R2 is a hydrogen atom, or a linear or branched C1-C4 alkyl group;
- R3 is:
- a C1-C18 alkyl group, a C3-C18 alkene group, or a C3-C4 alkyne group, said alkyl, alkene and alkyne groups being linear or branched and optionally substituted with a hydroxyl, a hydroxyphenyl or a dihydroxyphenyl group;
- or
- the side chain of an amino acid selected from the group consisting of tyrosine, hydroxyproline, serine, homoserine, isoserine, threonine, homothreonine and isothreonine;
- provided that said compound is not one of the following compounds:
- 2-cis-entadamide A, isopenangin, N-ethyl-cis-3-butylmercaptoacrylamide and N-ethyl-cis-3-methylmercaptoacrylamide.
A cosmetic or dermocosmetic composition useful for photoprotection, which comprises as main active ingredient a compound of formula (IIIa), a compound of formula (IIIb), or a mixture thereof, in combination with any additive physiologically compatible with skin or appendages:
- wherein:
- Y═S or SO;
- R1 is a linear or branched C1-C4 alkyl group;
- R2 is a hydrogen atom, or a linear or branched C1-C4 alkyl group;
- R3 is:
- a C1-C18 alkyl group, a C3-C18 alkene group, or a C3-C4 alkyne group, said alkyl, alkene or alkyne groups being linear or branched and optionally substituted with a hydroxyl, a hydroxyphenyl or a dihydroxyphenyl group;
- or
- the side chain of an amino acid selected from the group consisting of tyrosine, hydroxyproline, serine, homoserine, isoserine, threonine, homothreonine and isothreonine;
- and
- wherein the amount of main active ingredient is in the range from 0.001% to 0.1% by weight based on the total weight of the composition.
A method of photoprotection against sun radiation, which comprises applying to skin a cosmetic or dermocosmetic composition comprising, as main active ingredient, a compound of formula (IIIa), a compound of formula (IIIb), or a mixture thereof, in combination with any additive physiologically compatible with skin or appendages:
- wherein:
- Y═S or SO;
- R1 is a linear or branched C1-C4 alkyl group;
- R2 is a hydrogen atom, or a linear or branched C1-C4 alkyl group;
- R3 is:
- a C1-C18 alkyl group, a C3-C18 alkene group, or a C3-C4 alkyne group, said alkyl, alkene or alkyne groups being linear or branched and optionally substituted with a hydroxyl, a hydroxyphenyl or a dihydroxyphenyl group;
- or
- the side chain of an amino acid selected from the group consisting of tyrosine, hydroxyproline, serine, homoserine, isoserine, threonine, homothreonine and isothreonine.
Dependencies are inferred from the claim text.