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US 9,810,698 B2Granted
Neural proteins as biomarkers for nervous system injury and other neural disorders
AssigneesUniversity of Florida Research Foundation, Inc., Banyan Biomarkers, Inc.
InventorsKevin Ka-Wang Wang, Monika Oli, Ming-Cheng Liu
Life of this patent
Estimating the term…
Abstract
The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.
Claims5
A method for detecting Glial Fibrillary Acidic Protein (GFAP), comprising:
- detecting whether GFAP is present in a biological sample collected from a subject suspected of having a concussion by contacting the biological sample with an anti-GFAP antibody and detecting binding of the antibody to GFAP, wherein said biological sample is a blood, blood plasma, or serum sample, wherein the subject is not suspected of having an expanding hematoma, a subarachnoid hemorrhage, a cerebral edema, raised intracranial pressure (ICP), or cerebral hypoxia.
Dependencies are inferred from the claim text.