US 9,810,144 B2Granted

Process for the crystallisation of a water-soluble compound

AssigneeWageningen Universiteit

InventorsJohan Pieter Marinus Sanders, Marieke Elisabeth Bruins, Jeroen Johannes Cornelis Franciscus Van Bon

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Abstract

A process for the crystallisation of a water-soluble compound is disclosed. The process comprises (a) providing, in a crystallisation vessel, a solution of the water-soluble compound in a mixture of water and a solvent in which the water-soluble compound has a lower solubility than in water; (b) passing vapor phase of the mixture through a sorption zone containing a water vapor sorbent to selectively adsorb water from the vapor phase; (c) recycling a part of the vapor phase to the crystallisation vessel or withdrawing vapor phase depleted in water from the process and adding solvent to the crystallisation vessel; (d) allowing solid crystals of the water-soluble compound to precipitate from the solution; and (e) discharging precipitated solid crystals of the water-soluble compound from the crystallisation vessel and discharging a solution of non-crystallised water-soluble compound in water-solvent mixture from the crystallisation vessel.

Claims15

Dependent claims

A process for crystallisation of a water-soluble compound from a solution, comprising:

(a) providing, in a crystallisation vessel, a solution of the water-soluble compound in a mixture of water and a solvent, wherein the water-soluble compound has a lower solubility in the solvent than in water;
(b) passing vapour phase of the mixture through a sorption zone containing a water vapor sorbent to selectively adsorb water from the vapour phase to obtain a vapour phase depleted in water and enriched in the solvent and water-saturated water vapour sorbent;
(c) enriching the mixture in the crystallisation vessel in solvent by (i) recycling at least part of the vapour phase depleted in water and enriched in the solvent to the crystallisation vessel or (ii) withdrawing vapour phase depleted in water from the process and adding solvent from an external source to the crystallisation vessel;
(d) allowing solid crystals of the water-soluble compound to precipitate from the solution in the crystallisation vessel at a crystallisation temperature;
and
(e) discharging precipitated solid crystals of the water-soluble compound from the crystallisation vessel and discharging a solution of non-crystallised water-soluble compound in water-solvent mixture from the crystallisation vessel.

3 more elements

A process for the manufacture of a crystalline water-soluble compound from biomass, comprising:

(a1) extracting comminuted biomass containing said water-soluble compound with an aqueous liquid selected from water or a mixture of water and an alcohol with one to four carbon atoms or a mixture of two or more thereof, to obtain a solution of the water-soluble compound in the aqueous liquid and solid extracted biomass comprising remaining water-soluble compound;
(a2) separating the solution of said water-soluble compound from the solid extracted biomass;
and
(a3) supplying the solution to a crystallisation vessel or, in case the aqueous liquid is water, supplying both the solution and a stream of the alcohol to the crystallisation vessel;
(b) passing vapour phase of the mixture through a sorption zone containing a water vapour sorbent to selectively adsorb water from the vapour phase to obtain a vapour phase depleted in water and enriched in the solvent and water-saturated water vapour sorbent;
(c) enriching the mixture in the crystallisation vessel in solvent by (i) recycling at least part of the vapour phase depleted in water and enriched in the solvent to the crystallisation vessel or (ii) withdrawing vapour phase depleted in water from the process and adding solvent from an external source to the crystallisation vessel;
(d) allowing solid crystals of the water-soluble compound to precipitate from the solution in the crystallisation vessel at a crystallisation temperature;
and
(e) discharging precipitated solid crystals of the water-soluble compound from the crystallization vessel and discharging a solution of non-crystallised water-soluble compound in water-solvent mixture from the crystallisation vessel.

6 more elements

Dependencies are inferred from the claim text.

Facts

Application: 14/971,431Filed 16 Dec 2015 · continuation
Priority: NL 200644722 Mar 2011
Published: US 2016/0097321 A17 Apr 2016
Granted: 7 Nov 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

F02B 43/12
Engines or plants characterised by use of other specific gases, e.g. acetylene, oxyhydrogen: methods of operating
B01D 9/0054
Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction…
C07H 1/06
Processes for the preparation of sugar derivatives: separation; Purification
C07H 3/04
Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms: disaccharides

Family

PCT/NL2012/050169Parent of this continuation · filed 19 Mar 2012
US 2016/0097321 A1Pre-grant publication · published 7 Apr 2016
Application14/006,459Parent of this continuation
US 9,255,301 B2Parent of this continuation
US 2014/0087437 A1Published application
US 9,810,144 B2This patent

From the US filing history. Foreign family members aren’t listed.