Monascus strains modified for organic acid production
AssigneeTotal Research & Technology Feluy
InventorsAlexander Ruud Weusthuis, Emil Johan Harald Wolbert, Jan Springer, John Van Der Oost, Gerrit Eggink
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Abstract
The present invention provides tools and methods for producing organic acids using strains of Monascus which are tolerant to high organic acid concentrations at low pH.
Claims13
A genetically modified or recombinant micro-organism of the genus Monascus, wherein the micro-organism is tolerant to organic acid at a concentration of at least 50 g/L and a pH of less than 5.0, and wherein the micro-organism has been genetically modified for increased production of a lactic acid by the introduction of an exogenous lactate dehydrogenase (LDH) gene.
Dependencies are inferred from the claim text.