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US 9,809,825 B2Granted
Method for producing archaeal protein
AssigneeNational Institute of Advanced Industrial Science and Technology
InventorsKazuhiko Ishikawa, Seiichirou Kishishita, Tatsuya Fujii
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Abstract
An object of the present invention is to provide a means for producing an archaeal protein by extracellular secretion. The system for secretory production of an archaeal protein uses a fungus belonging to the genus Talaromyces as a host.
Claims16
A method of producing an archaeal protein, comprising a step of cultivating a fungus belonging to the genus Talaromyces,
- wherein the fungus has been transformed with an expression vector comprising:
- a promoter region that functions in the fungus;
- a secretion signal region located downstream of the promoter region, the secretion signal region encoding a secretion signal peptide of a cellobiohydrolase gene from the genus Talaromyces;
- a coding region for the archaeal protein located downstream of the secretion signal region;
- and
- a terminator region located downstream of the coding region, and
- wherein the fungus secretes the archaeal protein.
4 more elements
Dependencies are inferred from the claim text.