Anti-Staphylococcus antibody, method for manufacturing same, and usage of same
AssigneesZenyaku Kogyo Kabushiki Kaisha, Juntendo Educational Foundation
InventorsHiroyoshi Ohsawa, Jumpei Enami, Keiichi Hiramatsu
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Abstract
[Problem] The present invention addresses the problem of providing an anti-Staphylococcus antibody having preventive or therapeutic effects on staphylococcal infections. [Solution] Provided is an anti-Staphylococcus antibody having preventive or therapeutic effects on staphylococcal infections and a method for manufacturing said antibody, as well as a composition, a product, and a drug containing said antibody. The antibody is obtained by using deacetylated Staphylococcus for immunization.
Claims19
An antibody, comprising:
- a heavy chain variable region that comprises
- (i) CDRH1 of SEQ ID NO:
- 1, CDRH2 of SEQ ID NO:
- 2, and CDRH3 of SEQ ID NO:
- 3 or
- (ii) CDRH1 of SEQ ID NO:
- 9, CDRH2 of SEQ ID NO:
- 10, and CDRH3 of SEQ ID NO:
- 11;
- and
- a light chain variable region that comprises
- (i) CDRL1 of SEQ ID NO:
- 4, CDRL2 of SEQ ID NO:
- 5, and CDRL3 of SEQ ID NO:
- 6 or
- (ii) CDRL1 of SEQ ID NO:
- 12, CDRL2 of SEQ ID NO:
- 13, and CDRL3 of SEQ ID NO:
- 14.
An antibody produced by a hybridoma deposited under Accession Number:
- NITE BP-1367 or Accession Number:
- NITE BP-1366.
Dependencies are inferred from the claim text.