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US 9,809,626 B2Granted
Antibacterial agents: salinamide derivatives
AssigneeRutgers, The State University of New Jersey
InventorsRichard H. Ebright, Yon W. Ebright, Yu Feng, David Degen
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Abstract
The invention provides compounds of formula (I): and salts thereof, wherein X and Y have any of the values defined herein. The compounds inhibit bacterial RNA polymerase, inhibit bacterial growth, and have applications in, analysis of RNA polymerase structure and function, control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, antibacterial therapy, and drug discovery.
Claims3
A method for preparing a compound:
- the method comprising the step of deprotecting a compound:
- by removing the tert-butyloxycarbonyl (Boc) group.
A method for preparing a compound:
- the method comprising the step
- of deprotecting a compound:
- by removing the tert-butyloxycarbonyl (Boc) group.
A compound selected from:
- or a salt thereof.
Dependencies are inferred from the claim text.