Crystal form of regadenoson and preparation method thereof
AssigneeShanghai Ziyuan Pharmaceutical Co., Ltd.
InventorsWei Liu, Zhigang Zhang, Qin Bao
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Abstract
The present invention relates to the field of medicinal chemistry, and discloses a new crystal form of regadenoson, i.e., a crystal form E of regadenoson, as well as a method for preparing the new crystal form of regadenoson. The crystal form E of regadenoson according to the present invention has excellent performances in terms of radionuclide myocardial perfusion imaging, and has a poor toxicity, good storage stability, and can be used in the preparation of a medicament used as a stress agent for radionuclide myocardial perfusion imaging.
Claims6
A crystal form E of regadenoson, which is characterized in that, it has an X-ray powder diffraction pattern substantively as shown in FIG. 5;
- and
- an absorption peak at about 221.02° C. in differential scanning calorimetric analysis curve thereof.
Dependencies are inferred from the claim text.