Inhibitors of CXCR2

A compound having formula (I):

• wherein
• R1 and R2 are each members independently selected from the group consisting of H, halogen, CN, C1-4 alkyl, C1-4 alkoxy and C1-4 haloalkyl;
• R3a is a member selected from the group consisting of methyl, ethyl, propyl, isopropyl, trifluoromethyl, CH2CF3 and CF2CF3;
• R3b is a member selected from the group consisting of H and D;
• R4 is a member selected from the group consisting of H, C1-8 alkyl, —Y and C1-4alkylene-Y;
• wherein Y is aryl or heteroaryl, and each R4 is optionally substituted with from one to four substituents selected from the group consisting of halogen, —CN, —CO2Ra, —CONRaRb, —C(O)Ra, —OC(O)NRaRb, —NRaC(O)Rb, —NRaC(O)2Rc, —NRaC(O)NRaRb, —NRaRb, —ORa, —S(O)2NRaRb, —NRaS(O)2Rb, and —Rc,
• wherein each Ra and Rb is independently selected from hydrogen, C1-4 alkyl, C1-4 hydroxyalkyl and C1-4 haloalkyl, and Rc is selected from C1-4 alkyl;
• C1-4 hydroxyalkyl and C1-4 haloalkyl;
• R5a and R5b are each members independently selected from the group consisting of H, halogen, C1-4 alkyl, C1-4 alkoxy and CN;
• R6a and R6b are each members independently selected from the group consisting of H, C1-4 alkyl, C1-4 hydroxyalkyl and C1-4 haloalkyl;
• or optionally R6a and R6b are taken together to form oxo (═O);
• X is CH or N;
• or any salts, solvates, hydrates, N-oxides, tautomers or rotamers thereof.