Cartridges, collectors, kits, and methods for enhanced detection and quantification of analytes in collected fluid samples

A sample analysis cartridge comprising:

• an input tunnel that extends from an aperture, the input tunnel configured to permit insertion of a sample collection device having a distal portion adapted to be exposed to a fluid sample;
• a reservoir configured to hold a fluid;
• and
• a shuttle disposed in the input tunnel between the reservoir and the aperture in a first position, the shuttle comprising a body having a first end and a second end and defining a sample compartment between the first and second ends, the shuttle comprising an opening at the second end, the sample compartment configured to receive the fluid sample compressed from the distal portion of the sample collection device through the opening at the second end, the shuttle configured to move within the input tunnel when subjected to a force greater than a threshold force to a second position such that the sample compartment having the fluid sample is moved into the reservoir.