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US 9,808,539 B2Granted
Hypoosmotic solutions for lymph node detection
AssigneeEndomagnetics Ltd
InventorsAndrew P. Shawcross, John Gonzalez-Carvajal, Marc Brown, Rob Turner
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Abstract
Provided are compositions for rapid detection of lymph nodes. The compositions include magnetic particles, such as iron oxide, and a solute present in an amount that results in a hypoosomotic solution. Methods for detecting lymph nodes also are provided.
Claims14
A hypoosmotic suspension for medical injection comprising:
- about 13 mg/mL to about 200 mg/mL of superparamagnetic particles;
- and
- an osmolyte selected from either about 0.01% w/v to about 0.6% w/v of an inorganic salt or about 0.5% w/v to about 1.5% w/v of a glycol
- wherein the hypoosmotic suspension has an osmolality of about 80 mOsm/kg to about 160 mOsm/kg.
1 more element
Dependencies are inferred from the claim text.