Pharmaceutical kit and methods for cancer treatment via intracavity delivery and for preparing metal nanoparticle-antibody fragment conjugate

A method for cancer treatment via intracavity delivery, comprising the steps of:

• a) preparing a metal nanoparticle-antibody fragment conjugate, wherein the metal nanoparticle is modified with carboxyl group or polyethylene glycol (PEG) and covalently bound to the antibody fragment comprising sulfhydryl group, wherein said antibody fragment is one of a half-antibody fragment and a monoclonal antibody fragment;
• b) administering the conjugate to a cancer cell;
• and;
• c) providing a spherical or superficial green laser light source to irradiate the metal nanoparticle-antibody fragment conjugate bonded to the cancer cell.