Pharmaceutical combination comprising metformin and dihydroquercetin and its use for the treatment of cancer
AssigneeResearch Institute for Nutrition and Aging Co., Ltd.
InventorsKunihiko Kiyono, Kenji Onishi, Yasuharu Nagahama, Takashi Watanabe
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Abstract
Provided is a novel medicament capable of reducing the side effects of metformin or a pharmaceutically acceptable salt thereof and useful as an anti-malignant tumor agent, in which metformin or a pharmaceutically acceptable salt thereof and dihydroquercetin or a pharmaceutically acceptable salt thereof are combined.
Claims8
A method for treating a malignant tumor, comprising administering metformin or a pharmaceutically acceptable salt thereof, and dihydroquercetin or a pharmaceutically acceptable salt thereof to a subject in need thereof, wherein metformin or a pharmaceutically acceptable salt thereof, and dihydroquercetin or a pharmaceutically acceptable salt thereof are administered as a single preparation or separate preparations which are administered simultaneously or at different time points,
- wherein the malignant tumor is lung cancer, pancreatic cancer, liver cancer, breast cancer, prostate cancer, bile duct cancer, or ovarian cancer.
A method of suppressing a pancreatic cancer stem cell, comprising administering dihydroquercetin or a pharmaceutically acceptable salt thereof to a subject in need thereof.
Dependencies are inferred from the claim text.