Biomarker for parkinson's disease and use thereof
AssigneeTokyo Metropolitan Institute of Medical Science
InventorsNoriyuki Matsuda, Fumika Koyano, Kei Okatsu, Etsu Go, Mayumi Kimura, Yasushi Saeki
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Abstract
A antibody has as a target molecule a ubiquitin protein comprising a phosphorylated serine residue at position 65. In addition, a method is provided for specifically detecting Parkinson's disease at an early stage, in which a target molecule is a ubiquitin protein comprising a phosphorylated serine residue at position 65, a pharmaceutical composition for definitively treating or preventing Parkinson's disease, and a method for screening for the pharmaceutical composition.
Claims2
An antibody having an ability to specifically bind to a ubiquitin protein comprising a phosphorylated serine residue at position 65, wherein the antibody specifically binds to an epitope present within amino acid residues 59 to 69 of SEQ ID NO:1.
Dependencies are inferred from the claim text.