Immunoreactive antigens of Mycoplasma haemofelis and diagnostic immunoassay
AssigneePurdue Research Foundation
InventorsJoanne Belle Messick, Andrea Pires Santos
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Abstract
Compositions for use in diagnostic screens for Mycoplasma haemofelis are provided. In one embodiment an immunogenic peptide selected from SEQ ID NO: 1 to SEQ ID NO: 60, or a fragment thereof, is immobilized on a solid support and is used to detect the presence of Mycoplasma haemofelis antibodies in a patient bodily fluid. In accordance with one embodiment a method for detecting a Mycoplasma haemofelis infection in a feline species, is provided.
Claims21
A peptide complex comprising one or more different recombinant fusion peptides and a solid support, wherein the one or more recombinant fusion peptides each comprises
- an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1 through SEQ ID NO:
- 60 and a terminal amino acid sequence covalently linked at the carboxy or amino terminus of the one or more recombinant fusion peptides;
- wherein the one or more recombinant fusion peptides does not encode a native amino acid sequence of Mycoplasma haemofelis;
- and
- wherein the one or more recombinant fusion peptides are immobilized on the solid support.
A composition comprising two or more different isolated recombinant fusion peptides,
- wherein each of said isolated peptides comprises an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1 through SEQ ID NO:
- 60 and a terminal amino acid sequence covalently linked at the carboxy or amino terminus of the two or more isolated recombinant fusion peptides;
- and
- wherein the two or more isolated recombinant fusion peptides do not encode a native amino acid sequence of Mycoplasma haemofelis.
Dependencies are inferred from the claim text.