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US 9,804,145 B2Granted
Infrared analysis of benign tumors
AssigneeTodos Medical Ltd.
InventorsJoseph Kapelushnik, Shaul Mordechai, Ilana Nathan, Udi Zelig, Rami Zigdon
Life of this patent
Estimating the term…
Abstract
A method is provided comprising, obtaining an infrared (IR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample of a subject by analyzing the sample by infrared spectroscopy; analyzing the infrared spectrum using a processor (22), and based on the analyzing using the processor, using an output device (24), generating an output indicative of the presence of a benign tumor of the subject. Other applications are also described.
Claims16
A method comprising:
- identifying a subject as possibly having a benign tumor in breast tissue of the subject;
- obtaining an infrared (IR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample of the subject by analyzing the sample by infrared spectroscopy;
- assessing a characteristic of the sample at at least one wavenumber selected from the group consisting of:
- 837.4±4 cm-1, 1027.9±4 cm-1, 1182.6±4 cm-1, 1213.0±4 cm-1, 1278.1±4 cm-1, 1544.2±4 cm-1, 1011.0±4 cm-1, 1071.7 cm-1, 1141.7±4 cm-1, 1158.0±4 cm-1, 1181.7±4 cm-1, and 1502.3±4 cm-1;
- and
- using a processor comparing, at the at least one wavenumber, the infrared spectrum to an infrared spectrum obtained from a PBMC sample from a person without a benign tumor, to detect a difference between the infrared spectrum of the PBMC sample of the subject and the infrared spectrum obtained from the PBMC sample from the person without a benign tumor.
3 more elements
A method comprising:
- obtaining an infrared (IR) spectrum of a plasma blood sample of a subject by analyzing the sample by infrared spectroscopy;
- assessing a characteristic of the sample at at least one wavenumber selected from the group consisting of:
- 1402.5±4 cm-1, 1466.6±4 cm-1, 1587.1±4 cm-1, 1169.6±4 cm-1, 1674.9±4 cm-1, 1512.4±4 cm-1, 1267.0±4 cm-1, 1378.9±4 cm-1, 1404.9±4 cm-1, 774.3±4 cm-1, 1153.2±4 cm-1, and 992.7±4 cm-1;
- and
- using a processor comparing, at the at least one wavenumber, the infrared spectrum to an infrared spectrum obtained from a plasma sample from a person without a benign tumor, to detect a difference between the infrared spectrum of the plasma sample of the subject and the infrared spectrum obtained from the plasma sample from the person without a benign tumor.
2 more elements
A method comprising:
- identifying a subject as possibly having a benign tumor in gastrointestinal tract tissue of the subject;
- obtaining an infrared (IR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample of the subject by analyzing the sample by infrared spectroscopy;
- assessing a characteristic of the sample at at least one wavenumber selected from the group consisting of:
- 785.4±4 cm-1, 811.9±4 cm-1, 879.9±4 cm-1, 1253.0±4 cm-1, 1485.4±4 cm-1, 1526.9±4 cm-1, 760.8±4 cm-1, 870.7±4 cm-1, and 1485.9±4 cm-1;
- and
- using a processor comparing, at the at least one wavenumber, the infrared spectrum to an infrared spectrum obtained from a PBMC sample from a person without a benign tumor, to detect a difference between the infrared spectrum of the PBMC sample of the subject and the infrared spectrum obtained from the PBMC sample from the person without a benign tumor.
3 more elements
Dependencies are inferred from the claim text.