Systems and methods for multiplexed electrochemical detection
AssigneeThe Governing Council of the University of Toronto
InventorsShana O. Kelley, Edward Hartley Sargent, Brian Lam
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Abstract
Contemplated methods and devices comprise performing electrochemical sample analysis in a multiplexed electrochemical detector having reduced electrical cross-talk. The electrochemical detector includes electrodes that share a common lead from a plurality of leads. The sample, which may be a liquid sample, is introduced into one or more sample wells and a signal is applied to at least one of the electrodes. A response signal is measured while simultaneously applying a substantially fixed potential to each of a remainder of the plurality of leads.
Claims24
A method for performing electrochemical analysis, the method comprising:
- introducing a sample into a multiplexed electrochemical detector, the multiplexed electrochemical detector comprising a plurality of leads adapted to be electrically coupled to a first plurality of working electrodes, and a first counter electrode adapted to be electrically coupled to a second plurality of working electrodes, each of the first plurality of working electrodes housed in a different one of a plurality of sample wells, each of the second plurality of working electrodes housed in a first sample well of the plurality of sample wells;
- applying a first signal to a first lead of the plurality of leads;
- measuring a first response signal from the first counter electrode while simultaneous applying a substantially fixed potential to each of a first remainder of the plurality of leads;
- and
- determining whether a first target analyte is present in the sample based on the first response signal.
Dependencies are inferred from the claim text.