Integrated spectral probe for raman, reflectance and fluorescence spectral measurements
OwnerHaishan Zeng, Michael Short +1inventors
InventorsHaishan Zeng, Michael Short, Jianhua Zhao
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Abstract
Examples of a spectroscopy probe for performing measurements of Raman spectra, reflectance spectra and fluorescence spectra are disclosed. The integrated spectral probe can comprise one or more light sources to provide a white light illumination to generate reflectance spectra, an excitation light to generate an UV/visible fluorescence spectra and a narrow band NIR excitation to induce Raman spectra. The multiple modalities of spectral measurements can be performed within 2 seconds or less. Examples of methods of operating the integrated spectroscopy probe disclosed.
Claims16
An integrated spectroscopy system to facilitate integrated measurements of Raman spectra, reflectance spectra and fluorescence spectra, the system comprising:
- a light source configured to provide a white light illumination beam to generate reflectance spectra, an excitation light beam to generate an UV/visible fluorescence spectra and a narrow band excitation light beam to induce Raman spectra;
- an integrated spectroscopy probe coupled to the light source, the spectroscopy probe comprising:
- at least one narrow band excitation fiber configured to transmit the narrow band excitation light beam to a target;
- at least one white light illumination fiber configured to transmit the white light illumination beam to the target;
- at least one excitation illumination fiber configured to transmit the excitation light beam to the target;
- a plurality of Raman collection fibers configured to collect a returning radiation reflected and emitted from the target in response to the narrow band excitation light beam;
- at least one reflectance collection fiber configured to collect a returning radiation reflected from the target in response to the white light illumination beam;
- and
- at least one fluorescence collection fiber configured to collect returned radiation emitted from the target in response to the excitation light beam;
- a first detector coupled to the plurality of Raman collection fibers to detect a Raman spectrum;
- and
- at least one additional detector coupled to the at least one reflectance collection fibers and/or the at least one fluorescence collection fibers to detect a reflectance spectrum and/or a fluorescence spectrum,
- wherein the at least one white light illumination fiber, the at least one excitation illumination fiber, the at least one reflectance collection fiber and the at least one fluorescence collection fiber are placed between the at least one narrow band excitation fiber and the plurality of Raman collection fibers and are each spaced apart from the at least one narrow band excitation fiber and the plurality of Raman collection fibers.
Dependencies are inferred from the claim text.