US 9,804,070 B2Granted

Biological fluids concentration assembly

AssigneeAlliance Partners LLC

InventorsEmad Hassouneh, Logan White, Matt Schmidt, Andrew Enke, Frank Morris

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Abstract

A biological fluids concentration device, including a tube-in-tube assembly, is disclosed. The tube-in-tube assembly receives biologic fluids and may then be placed in the bucket of a centrifuge and spun to separate out the components of the biological fluid by their various densities. For example, whole blood may be centrifuged in the tube-in-tube assembly for separating into plasma, red blood cell component, and a buffy coat. A piston slideably and sealingly engages an inner tube of the tube-in-tube assembly, the inner tube fitting within an outer tube. A lid is designed to engage the top of the outer tube, which lid has an opening therein for receipt of a plunger. The plunger is adapted to move up and down with respect to the lid and the tubes, so as to sealingly, in a down position, and unsealingly, in an open position, engage the top of the inner tube of the tube-in-tube assembly.

Claims10

Dependent claims

A biological fluids concentration assembly comprising:

a tube-in-tube assembly defining a vertical axis and comprising a cylindrical outer tube and a cylindrical inner tube having inner walls, both tubes having open tops and both having cylinder bottoms, the open top of the inner cylinder being located below the open top of the outer cylinder;
a piston for slidably and fluid sealingly engaging the inner walls of the inner tube below the open top;
a lid having a body and a perimeter for engaging the open top of the outer tube, the lid having a bore located in the body thereof;
a plunger capable of moving longitudinally with respect to the tube-in-tube assembly, the plunger having a body and a base, the plunger having a channel extending therethrough, the body dimensioned for moving longitudinally through the bore of the lid, the base configured to sealingly engage the open top of the inner tube, the channel of the plunger having an exterior opening that opens to the open top and an interior opening, opening to an interior of the tube-in-tube assembly;
and
an assembly for engagement with the tube-in-tube assembly to move the plunger towards the open top of the inner tube.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application: 14/226,248Filed 26 Mar 2014 · us provisional application
Priority: 26 Mar 2013
Published: US 2015/0004079 A11 Jan 2015
Granted: 31 Oct 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification16 codes

G01N 1/4077
Concentrating samples: by other techniques involving separation of suspended solids
B01L 3/5021
With fluid transport, e.g. in multi-compartment structures: test tubes specially adapted for centrifugation purposes
A61M 1/3693
Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood…
A61M 1/67
Containers with integrated suction means: containers incorporating a piston-type member to create suction, e.g. syringes