Methods for producing biological materials
AssigneePalo Alto Investors
InventorAnthony Joonkyoo Yun
Life of this patent
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Abstract
Methods of producing biological materials from cells and organisms are provided. Aspects of the methods include modulating the stress conditions of the cells and/or organism to produce biological materials having one or more desired properties. In certain aspects, the cell or organism is evaluated to detect the presence or absence of a stressed phenotype, wherein an unstressed phenotype may be produced before the cell or organism produces the biological material of interest. The biological materials produced from such cells and organisms may be used for a variety of applications, including therapeutic, research, and other applications.
Claims20
A method for producing a biological product from a cell, the method comprising:
- culturing the cell containing a nucleic acid encoding at least a portion of the biological product, under conditions that modulate a stressed phenotype of the cell and allow for expression of the biological product, wherein the produced biological product is different from the biological product produced in a control cell having the stressed phenotype as compared to the cell;
- evaluating the cell to identify the absence of the stressed phenotype;
- and
- recovering the biological product.
Dependencies are inferred from the claim text.