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AssigneesResearch Institute of Innovative Technology for the Earth, Sumitomo Rubber Industries, Ltd.
InventorsKeitarou Fujikura, Kazumi Hiraga, Masayuki Inui, Hideaki Yukawa
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An objective of the present invention is to provide a microorganism capable of efficiently producing aniline from aminobenzoic acid, and a process for efficiently producing aniline from aminobenzoic acid. To achieve the objective, provided is an aniline-producing transformant constructed by introducing a gene which encodes an enzyme having aminobenzoate decarboxylase activity into a coryneform bacterium as a host, characterized in that the enzyme having aminobenzoate decarboxylase activity is composed of an amino acid sequence which is the same as that represented by SEQ ID NO: 2 except for having a mutation of at least proline (P) at position 309 from the N terminus.
A Corynebacterium transformant that produces aniline from 4-aminobenzoic acid, wherein the transformant is transformed with a polynucleotide encoding an enzyme having aminobenzoate decarboxylase activity, wherein the amino acid sequence of the enzyme is a variant of the amino acid sequence of SEQ ID NO:
A Corynebacterium glutamicum transformant selected from the group consisting of the Corynebacterium glutamicum having National Institute of Technology and Evaluation (MITE) Accession Number BP-01583, the Corynebacterium glutamicum having NITE Accession Number BE-01584, and the Corynebacterium glutamicum having NITE Accession Number BP-01585.
Dependencies are inferred from the claim text.