US 9,803,199 B2Granted

Cationic lipid

AssigneeDaiichi Sankyo Company, Limited

InventorsMakoto Koizumi, Yoshiyuki Onishi, Takako Niwa, Masakazu Tamura, Yuji Kasuya

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Abstract

The present invention provides a compound represented by the formula (Ia) as a novel cationic lipid that forms a lipid particle and also provides a lipid particle comprising the compound. The present invention further provides a nucleic acid lipid particle containing the lipid particle, and a pharmaceutical composition containing the nucleic acid lipid particle as an active ingredient.

Claims29

Dependent claims

A lipid having the formula:

or a pharmacologically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 14/903,711Filed 7 Jul 2014
Priority: JP 2013-1426778 Jul 2013
Published: US 2016/0257951 A18 Sep 2016
Granted: 31 Oct 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification28 codes

C12N 15/113
DNA or RNA fragments; Modified forms thereof ; Non-coding nucleic acids having a biological activity: non-coding nucleic acids modulating the…
A61K 9/10
Medicinal preparations characterised by special physical form: dispersions; Emulsions
A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 9/1271
Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant: non-conventional liposomes,…

Family

US 2016/0257951 A1Pre-grant publication · published 8 Sep 2016
US 9,803,199 B2This patent

From the US filing history. Foreign family members aren’t listed.

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