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US 9,803,027 B2Granted
Method for decreasing immunogenicity
AssigneeESBATech, an Alcon Biomedical Research Unit LLC
InventorsDavid Urech, Leonardo Jose Borras
Life of this patent
Estimating the term…
Abstract
A method for decreasing the immunogenicity of antibody variable domains is disclosed.
Claims2
A single chain antibody (scFv), wherein the scFv comprises a variable light chain comprising a serine at position 101 (Aho numbering) and a variable heavy chain comprising Serine (S) at heavy chain amino acid position 12, Threonine (T) at heavy chain amino acid position 103, and Threonine (T) at heavy chain amino acid position 144 (AHo numbering).
Dependencies are inferred from the claim text.