Fusion proteins for the treatment of allergic diseases
AssigneeVeterinaerinstituttet
InventorsMaaike Maria Barbara Wilhelmina Dooper, Bjarne Bogen, Heidi Ragnhild Myrset
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Abstract
The present invention relates to a fusion protein comprising a first peptide and a second peptide linked together with a linker, wherein the first peptide is an allergen and the second peptide is a targeting unit and the targeting unit is a FGL-2 C-terminal peptide according to SEQ ID no 1. Provided herein are also uses of said fusion protein as a vaccine for treating allergy, such as shrimp, peanut or mite allergy, as well as a vaccine composition and methods for producing such fusion proteins.
Claims17
A fusion protein comprising a first peptide and a second peptide optionally linked together with a linker, wherein the first peptide is an allergen and the second peptide consists of an amino acid sequence selected from the group consisting of SEQ ID NO:1 and sequences that are at least 95% identical to SEQ ID NO:1.
Dependencies are inferred from the claim text.