Immunogenic fusion polypeptides
AssigneePfizer Inc.
InventorsDeborah Ann Dilts, Annaliesa Sybil Anderson, Kathrin Ute Jansen, Justin Keith Moran, Mark E Ruppen, Eugene Joseph Vidunas
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Abstract
In one aspect, the invention relates to an isolated polypeptide including the amino acid sequence of a carrier polypeptide and the amino acid sequence of an ORF2086 polypeptide. In another aspect, the invention relates to an immunogenic conjugate including ORF2086 polypeptide and a carrier polypeptide. The invention further includes immunogenic compositions and methods for inducing an immune response against Neisseria meningitidis in a mammal.
Claims6
An isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
- 2.
An isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
- 8.
An isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
- 14.
An isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
- 16.
An isolated polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
- 18.
Dependencies are inferred from the claim text.