Back to results
US 9,802,985 B2Granted
Pharmaceutical composition for treatment of the pulmonary form of altitude sickness caused by lack of oxygen and reduced air pressure
AssigneeApeptico Forschung Und Entwicklung GmbH
InventorsBernhard Fischer, Rudolf Lucas, Hendrik Fischer
Life of this patent
Estimating the term…
Abstract
What is described is a peptide which consists of 7-20, especially 7-17, adjacent amino acids and comprises the hexamer TX1EX2X3E where X1, X2 and X3 may be any natural or unnatural amino acid, where the peptide does not have any TNF receptor binding activity and is cyclized, for use for the treatment and avoidance of the pulmonary form of altitude sickness.
Claims10
A method for therapeutic treatment of the pulmonary form of altitude sickness, comprising
- administering to a patient having the pulmonary form of altitude sickness an effective amount of a peptide,
- wherein the peptide is 17-20 amino acids in length and comprises the amino acid sequence
- CGQREFPEGAEAKPWYC (SEQ ID NO:
- 1),
- wherein the peptide does not have tumor necrosis factor receptor binding activity,
- wherein the peptide is cyclized, and
- wherein the peptide is formulated in a nebulizble powder formulation.
4 more elements
A method for therapeutic treatment of the pulmonary form of altitude sickness, comprising
- administering by inhalation an effective amount of a peptide to a patient having the pulmonary firm of altitude sickness, wherein the pulmonary form of altitude sickness is treated by said administering,
- wherein the peptide consists of the amino acid sequence CGQRETPEGAEAKPWYC (SEQ ID NO:
- 1) and is cyclized via the C residues, and
- wherein the peptide is formulated as a powder for inhalation.
1 more element
Dependencies are inferred from the claim text.