Functional lipid constructs
AssigneeKode Biotech Limited
InventorsNicolai Vladimirovich Bovin, Stephen Micheal Henry, Igor Leonidovich Rodionov, Cristina-Simona Weinberg, Alexander Borisovich Tuzikov
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Abstract
The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In particular, the invention relates to functional lipid constructs and their use in diagnostic and therapeutic applications, including serodiagnosis, where the functional moiety is a carbohydrate, peptide, chemically reactive group, conjugator or fluorophore.
Claims4
A functional lipid construct of the structure:
- where L is phosphatidylethanolamide;
- M is CH3 or H;
- g is the integer 1, 2 or 3;
- h is the integer 1, 2, 3 or 4;
- v is the integer 3, 4 or 5;
- and Func-S1 is selected from the group consisting of:
- where w is the integer 1 or 2 and Func is S of a cysteine residue of a peptide;
- and
- where k is the integer 3, 4, or 5.
Dependencies are inferred from the claim text.