Chromatography medium
AssigneePuridify Ltd.
InventorsDaniel Gilbert Bracewell, Robert Stevens, Oliver Hardick
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Abstract
The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibers which form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same in chromatography, such as the isolation of recombinant proteins, monoclonal antibodies, viral vaccines and plasmid DNA. The invention further provides for the use of the chromatographic medium in a simulated moving bed system.
Claims16
A method for isolating a target molecule by ion-exchange chromatography, which method comprises using a chromatography medium comprising one or more non-woven electrospun cellulose nanofibres which are fused together at points where the nanofibres intersect one another and which in use form a stationary phase in the form of a membrane comprising a plurality of pores through which a mobile phase can permeate.
Dependencies are inferred from the claim text.